A patient-like swine model of gastrointestinal fibrotic strictures for advancing therapeutics
Abstract Gastrointestinal (GI) strictures are difficult to treat in a variety of disease processes.Currently, there are no Food and Drug Administration (FDA) approved drugs for fibrosis in the GI tract.One of the limitations to developing anti-fibrotic drugs has been the lack of a reproducible, relatively inexpensive, large animal model Sneakers fo